5 Simple Techniques For akorn promethazine codeine
5 Simple Techniques For akorn promethazine codeine
Blog Article
It's doable to become hooked on codeine. Due to this, your dose will be reviewed to ensure you're only having the amount you might want to Manage your discomfort.
There isn't any accessible information with promethazine HCl and codeine phosphate oral Answer use in pregnant Females to tell a drug-related chance for adverse developmental outcomes.
8.7 Hepatic Impairment No formal scientific tests are already done in individuals with hepatic impairment so the pharmacokinetics of promethazine HCl and codeine phosphate oral Alternative On this individual inhabitants are unknown.
Doses higher than sixty mg haven't been revealed to enhance agony reduction and so are associated with an elevated incidence of adverse effects.
Furthermore, the usage of opioids like codeine could cause dry mouth, which can lead to an increase in the number of dangerous teeth and gum-harmful microorganisms.
Like other opioids, codeine use carries a threat of overdose and poisoning when you consume a lot more than advisable. Signs or symptoms of overdose include things like:
Be sure that clients have an oral dosing dispenser that actions the suitable volume in milliliters. Counsel clients regarding how to make the most of an oral dosing dispenser and correctly measure the oral suspension as prescribed.
Phone your Health care supplier or get unexpected emergency healthcare enable right away if anybody using Promethazine with Codeine Oral Alternative, or your breastfeeding child has any of your signs and symptoms beneath: amplified sleepiness
Get in touch with local condition professional licensing board or state managed substances authority for info on how to stop and detect abuse or diversion of the merchandise.
five.2 Life-Threatening Respiratory Melancholy Significant, life-threatening, or lethal respiratory depression has long been described with the use of opioids, together with codeine, among the list of active elements in promethazine HCl and codeine phosphate oral Remedy. Codeine provides dose-relevant respiratory despair by right performing within the Mind stem respiratory center that controls respiratory rhythm and should produce irregular and periodic respiration. Codeine is issue to variability in metabolism based mostly on CYP2D6 genotype, which may result in an increased exposure to your active metabolite morphine [see Warnings and Precautions (5.
For instance, someone that snorts regular cocaine may be able to take care of a few strains. When they try to do the exact same with pure cocaine, it can cause overdose that results check here in cardiac arrest and Loss of life.
We foresee reposting the images after we've been able discover and filter out images that do not match the information furnished in the drug labels. NDC Codes
Promethazine hydrochloride was not mutagenic from the in vitro bacterial reverse mutation assay or clastogenic within the in vitro Chinese hamster ovary (CHO) cell chromosomal aberration assay.
No certain drug conversation research are conducted with promethazine HCl and codeine phosphate oral Resolution.